Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is a disease that is characterized by elevated calcium and parathyroid hormone levels. The most common cause of PHPT is the paratiroid adenoma and the first line treatment option is surgical removal of the adenoma. Rarely, the haemorrhage in the lesion may cause the spontaneous remission of the disease.Case report: A 54-year-old woman patient with fatigue was referred to our department due to calcium level...

Introduction: Struma ovarii is an uncommon ovarian neoplasm that more than half of itself is made up of thyroid tissue. In clinical trials about the disease, malign transformation has been detected at the rate of 0.5–5%. Because of the disease’s rareness, there is no absolute agreement about diagnosis and treatment of the disease.Case report: A 33-year-old woman admitted to gynecology department with abdominal pain. Her pelvic MR revealed 147&#...

Silent thyroiditis is characterized by the destructive thyroid inflammation and is considered to be a chronic autoimmune thyroid disease, although the etiology could not have been fully explained. On the other hand, Graves’ disease is autoimmune phenomena as well as silent thyroiditis and silent thyroiditis has been classified as part of the spectrum of Graves’ disease. Although, the thyroid stimulating antibody (TSAb) are found positive in most of Graves’ disea...

Androgenic alopecia (AGA) is an important clinical issue that can cause significant cosmetic problems. Many factors such as genetic, androgen hormones, environmental factors, and inflammation are involved in the pathogenesis of androgenic alopecia. Insulin and insulin resistance have been found increased in individuals with AGA. There are many proinflammatory substances which are playing role in the pathogenesis of androgenic alopecia. Secreted frizzled related protein-4 (SFRP...

Macro TSH is a large molecular-sized thyroid-stimulating hormone (TSH) that is including TSH and anti-TSH antibody. Patients with macro TSH have elevated serum TSH and normal free thyroxine levels similar to subclinical hypothyroidism. A 18-year old female patient was referred from gynecology and obstetrics to endocrinology clinic for evaluating of elevated TSH with normal free thyroxine levels. Laboratory and clinical investigations revealed that only discordant TSH levels (n...

Background: Netrin-1 is an early biomarker of acute kidney injury. Besides, recent studies have showed that netrin-1 promotes angiogenesis; but its usefulness for peripheral artery disease (PAD) in type 2 diabetes patients is unknown.This study aimed at investigating whether netrin-1 levelsare increased in peripheral artery disease among patients with type 2 diabetes and also investigating possible associationsbetween diabetic nephropathy (DN) and PAD.Ma...

Aim: Thirty female Wistar albino rats with surgically endometriotic implants were randomly randomized into three treatment groups: oral rosuvastatin (20 mg kg per day; oral rosuvastatin group 1; n=10), oral progesterone (Dienogest group 2; n=10), and intraperitoneal bevacizumab (2.5 mg/kg of single intaperitoneal injection of bevacizumab; group 3; n=10) respectively, for 10 day and post-treatment variables were compared.Results...